SAT Question ecb31049: Transitions answer and explanation

English - Transitions - Concession Transition
0:00
FREE OFFICIAL BANK
The Sun and other stars are powered by nuclear fusion reactions, in which two atoms collide to form a single heavier atom, releasing energy. Scientists have long believed that fusion has the potential to meet humanity’s clean energy needs. ______ prior to December 2022, no fusion reaction in a laboratory setting had ever generated a net energy gain.
177
Difficulty:Hard
Which choice completes the text with the most logical transition?