SAT Question fe41f258: Boundaries answer and explanation

English - Boundaries - Comma With Supplementary Element
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In ancient Greece, an Epicurean was a follower of Epicurus, a philosopher whose beliefs revolved around the pursuit of pleasure. Epicurus defined pleasure as “the absence of pain in the body and of trouble in the ______ that all life’s virtues derived from this absence.
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Difficulty:Medium
Which choice completes the text so that it conforms to the conventions of Standard English?